(1S,2R,3R)-Aprepitant

Product Name: (1S,2R,3R)-Aprepitant
CAS No.: 1242175-34-3
Chemical Name: (1S,2R,3R)-Aprepitant
Synonyms: Aprepitant Impurity 7;Aprepitant impurity 05;Aprepitant iMpurity 31;(2R,3R,1’S)-Aprepitant;Aprepitant (S,R,R)-Isomer;Aprepitant Impurity 4(S,R,R-Isomer);Aprepitant impurity 8/(1S,2R,3R)-Aprepitant;5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber: CB83146509
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 1242175-34-3.mol

More

Less

(1S,2R,3R)-Aprepitant Property

Density: 1.51±0.1 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: A729765
Product name: (2R,3R,1’S)-Aprepitant
Packaging: 1mg
Price: $130
Updated: 2021/12/16

More

Less

(1S,2R,3R)-Aprepitant Chemical Properties,Usage,Production

Uses

(2R,3R,1’S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2R,3R)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(1S,2R,3R)-Aprepitant Suppliers

China 32 India 3 United States 4 Global 39

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10413
Advantage: 58

1242175-34-3, (1S,2R,3R)-AprepitantRelated Search:

(S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one (2R)-4-BENZYL-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}MORPHOLIN-3-ONE Aprepitant Fosaprepitant dimeglumine (R,R,R)-Aprepitant 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Fosaprepitant Impurity 6 1,1,1-Trimethoxy-2-chloroethane Fosaprepitant Impurity 5 Fosaprepitant (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Aprepitant Impurity 9 Aprepitant Defluoro Aprepitant Aprepitant Impurity B HCl 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

Aprepitant Impurity 7

5-[[(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

Aprepitant (S,R,R)-Isomer

(2R,3R,1’S)-Aprepitant

Aprepitant iMpurity 31

Aprepitant Impurity 4(S,R,R-Isomer)

Aprepitant impurity 8/(1S,2R,3R)-Aprepitant

5-([(2R,3R)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one

3H-1,2,4-Triazol-3-one, 5-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

Aprepitant impurity 05

1242175-34-3